McKeesport, Pennsylvania Clinical Trials

A listing of McKeesport, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 58 clinical trials
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

UPMC Hillman Cancer Center
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
A Study of SBT6050 in Patients With Advanced HER2 Expressing Solid Tumors

A first-in-human (FIH) study using SBT6050 in HER2 expressing advanced malignancies

cancer
solid tumor
pembrolizumab
solid tumour
measurable disease
Investigative Site
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
The EMS Sleep Health Study: A Randomized Controlled Trial

The experiment seeks to determine the impact of a sleep health and fatigue education and training program on diverse indicators of sleep and fatigue among Emergency Medical Services (EMS) personnel. The overarching goals of this research study are to [1] enhance our understanding of the relationships between shift work, sleep, …

fatigue
University of Pittsburgh
 (8.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
cardiac arrest
resuscitation
induced hypothermia
life support
University of Pittsburgh Medical Center
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
Preferred Primary Care Physicians
 (6.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Testing Legally Feasible Options: Study 1

The overall aim of this research is to experimentally evaluate different, legally-viable approaches to reducing the impact of the point-of-sale (POS) retail environment on adolescent tobacco use risk. This study will be investigating the regulations for four classes of tobacco products (cigarettes, e-cigarettes, smokeless tobacco, little cigars/cigarillos). Study 1 (study …

tobacco product
RAND
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Semantic Feature Analysis Treatment for Aphasia

This randomized controlled comparative effectiveness study examines manipulation of a key component of an established and efficacious treatment for naming impairments in aphasia, along with cognitive and brain correlates of treatment success. Study participants will be randomly assigned to one of two treatment conditions comparing two different versions of Semantic …

brain imaging
migraine
treatment schedule
manipulation
aphasia
VA Pittsburgh Healthcare System
 (9.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

folic acid
cancer
lung cancer
infrared imaging
wedge resection
University of Pittsburgh Medical Center
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

gene amplification
cancer
exhausted
measurable disease
HER2
Bolt Investigative Site
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Predictors of Response in Chronic Stroke

This study will validate a predictive model that uses demographics, functional status, neurophysiology, neuroanatomy, and other potential biomarkers to predict the likelihood of a clinically significant change in impairment at the end of a robot assisted therapy intervention.The study will include magnetic resonance imaging (MRI), transcranial magnetic stimulation (TMS), and …

MRI
chronic stroke
arm exercises
arm exercise
stroke
VA Pittsburgh Healthcare System
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location