Bryn Mawr, Pennsylvania Clinical Trials

A listing of Bryn Mawr, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 86 clinical trials
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

abscess
antibiotic
antibiotic therapy
bimekizumab
antibiotics
Hs0004 50150
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification

Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions

University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

This is a pilot study using cytotoxic T lymphocytes (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Gamma-capture system will be effective in decreasing specific viral load in patients with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.

Children's Hospital of Philadelphia
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19

The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19. Blood tests will be done to check how much LY3819253 is in the bloodstream and how long the body takes to eliminate …

blood test
covid-19
Temple Univ School of Med
 (9.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

cyclosporine
estimated creatinine clearance
covid-19
cyclosporin a
oxygen supplementation
University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

oximetry
nasopharyngeal swab
SARS
nasal swab
covid-19
Temple University Hospital
 (9.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19 infection. In addition to SOC, the brequinar group will receive 5 daily doses of brequinar 100 mg.

coronavirus infection
pharyngitis
fraction of inspired oxygen (fio2)
gastrointestinal symptoms
dyspnea
Temple University
 (9.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test1a
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
API Trial-T1

API Trial-T1

Test AP Sit1
 (8.4 away) Contact site
  • 0 views
  • 18 Sep, 2024
  • 1 location