Bala-Cynwyd, Pennsylvania Clinical Trials

A listing of Bala-Cynwyd, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 111 clinical trials
Using Direct Brain Stimulation to Study Cognitive Electrophysiology

This project forms a multi-site research collaboration to carry out verbal and spatial memory experiments in patient volunteers to better understand the neural bases of human memory, employing direct electrical brain stimulation as a tool to study those dynamics and their relationship to memory performance.

brain stimulation
epilepsy
electrical stimulation
Thomas Jefferson University Hospital
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

This is a pilot study using cytotoxic T lymphocytes (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Gamma-capture system will be effective in decreasing specific viral load in patients with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.

Children's Hospital of Philadelphia
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19

The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19. Blood tests will be done to check how much LY3819253 is in the bloodstream and how long the body takes to eliminate …

blood test
covid-19
Temple Univ School of Med
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Phase I Study in Advanced Malignancies

RDT aims to take advantage of the relatively safer toxicity profiles of both lower dose radiation therapy and systemic ALA to treat non-superficial lesions in a manner similar to photodynamic therapy. The doses of radiation administered in this study will be lower than those typically used to treat cancer. However, …

red blood cell transfusion
investigational therapies
blood transfusion
metastasis
hair thinning
Fox Chase Cancer Center
 (8.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

cyclosporine
estimated creatinine clearance
covid-19
cyclosporin a
oxygen supplementation
University of Pennsylvania
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

oximetry
nasopharyngeal swab
SARS
nasal swab
covid-19
Temple University Hospital
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) Before and During Treatment With Ocrelizumab

This is an open-label, multicenter study that includes a main study for all participants enrolled and an optional cerebrospinal fluid (CSF) sub-study. Self-identified African American (AA) and Hispanic or Latin American (HA) participants with a diagnosis of relapsing multiple sclerosis (RMS) will be enrolled. The treating neurologist must make an …

Jefferson University Hospitals, Thomas Jefferson University
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +30 other locations
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19 infection. In addition to SOC, the brequinar group will receive 5 daily doses of brequinar 100 mg.

coronavirus infection
pharyngitis
fraction of inspired oxygen (fio2)
gastrointestinal symptoms
dyspnea
Temple University
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test1a
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations