Cleveland, Ohio Clinical Trials

A listing of Cleveland, Ohio clinical trials actively recruiting patient volunteers.

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Found 60 clinical trials
T3-S3-UK

Testing

Accepts healthy volunteers
Online studies
UK Site
(online study) Contact site
  • 0 views
  • 16 May, 2025
  • 1 location
  • Online study
UAT_Local 01-19-May  

This is for UAT_Local 01-19-May.

Accepts healthy volunteers
Online studies
UAT-UK
(online study)
  • 0 views
  • 19 May, 2025
  • 1 location
  • Online study
Test

In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Online studies
  • 0 views
  • 28 Aug, 2025
  • Online study
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Accepts healthy volunteers
Online studies
  • 0 views
  • 02 Apr, 2026
  • Online study
MMAPPIN' Study: Multiple Myeloma Analysis For Patient-specific Insights to Dissect Disease Heterogeneity  

This is a single-center, observational study in patients with multiple myeloma, conducted both retrospectively and prospectively. The study aims to improve understanding of the biological and clinical factors that influence disease progression, relapse, and treatment resistance.The study will integrate clinical information with advanced genomic and molecular analyses, including whole genome …

Online studies
  • 0 views
  • 10 Aug, 2026
  • Online study
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

mental state examination
alzheimer's disease
apolipoprotein e4
mini-mental state examination
Accepts healthy volunteers
University Hospitals Cleveland Medical Center / Case Western Reserve University
 (6.2 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
Enfortumab Vedotin and Pembrolizumab With or Without Chemotherapy vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together alone or with platinum chemotherapy to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients …

cancer
systemic therapy
immunomodulators
measurable disease
carboplatin
The Cleveland Clinic
 (1.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +25 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

marginal zone lymphoma
systemic therapy
lymphoma
malt
cyclophosphamide
Cleveland Clinic - Taussig Cancer Institute
 (1.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +35 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

connective tissue disease
patent ductus arteriosus
heart disease
ventricular septal defect
atrial septal defect
Cleveland Clinic
 (1.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +210 other locations
A Study of Oral Upadacitinib Tablet Compared to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa to Assess Change in Disease Symptoms

Hidradenitis suppurativa (HS) is an inflammatory skin disease that causes painful lesions in the axilla (underarm), inguinal (groin) and anogenital (anal and genital) regions. This study will evaluate how well upadacitinib compared to placebo (no medicine) works to treat hidradenitis suppurativa (HS) in adult participants with moderate to severe disease. …

University Hospitals Case Medical Center /ID# 218326
 (1.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +27 other locations