CINNCINATI, Ohio Clinical Trials

A listing of CINNCINATI, Ohio clinical trials actively recruiting patient volunteers.

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Found 60 clinical trials
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
pick's disease
aphasia
progranulin
University Of Cincinnati Gardner Neuroscience institute
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

migraine
lasmiditan
preventive medication
ly573144
headache
Cincinnati Childrens Hospital Medical Center
 (3.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
Engaging Adolescents in Decisions About Return of Genomic Research Results

Recent recommendations to return children's results for adult-onset conditions to parents anytime whole exome or genome sequencing is performed, as well as growing expectations to return research results to participants on a large-scale basis, mean adolescents will increasingly be engaged in assenting (<age 18) and consenting (>age 18) to return …

Cincinnati Children's Hospital Medical Center
 (3.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
cardiac arrest
resuscitation
induced hypothermia
life support
University of Cincinnati
 (2.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

platelet count
immunodeficiency
lung non-small cell squamous carcinoma
stage ii lung cancer ajcc v7
pemetrexed
Good Samaritan Hospital - Cincinnati
 (2.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +358 other locations
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection

Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19. Beyond supportive care, there are no proven treatment options for COVID-19.

SARS
absolute lymphocyte count
fraction of inspired oxygen (fio2)
oximetry
x-rays
Good Samaritan Hospital
 (2.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.

ttfields
malignant glioma
triamcinolone topical
triamcinolone
clindamycin
University of Cincinnati Medical Center
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Cysteamine for Asthma

The purpose of this study is to see if a medicine called Cysteamine, given along with standard asthma care, will improve asthma symptoms and lung function.

rhinitis
skin prick test
pulmonary function test
skin prick
allergen
Cincinnati Children's Hospital Medical Center
 (3.8 away) Contact site
  • 14 views
  • 24 Nov, 2025
  • 1 location
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by open-label naturalistic follow-up.

antidepressants
duloxetine
evra
oral contraceptives
depressive symptoms
University of Cincinnati
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam or pregabalin for persistent symptoms.

depression
duloxetine
depressive disorder
evra
pregabalin
University of Cincinnati, Department of Psychiatry & Behavioral Neuroscience
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location