Clifton, New Jersey Clinical Trials

A listing of Clifton, New Jersey clinical trials actively recruiting patient volunteers.

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Found 47 clinical trials
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

haemophilia a
bethesda assay
hemophilia
antihemophilic factor
fitusiran
Investigational Site Number 8400008
 (5.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Multi-center Open-label Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)

Primary Objectives: To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV) To evaluate the pharmacokinetics (PK) of SC and IV isatuximab Secondary Objectives: To estimate absolute bioavailability of SC and IV isatuximab To measure receptor occupancy (RO) after isatuximab SC versus IV administration To assess …

proteasome inhibitor
lenalidomide
measurable disease
corticosteroids
parenteral administration
Investigational Site Number 8400006
 (5.0 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +13 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

haemophilia a
bethesda assay
hemophilia
antihemophilic factor
fitusiran
Investigational Site Number 8400008
 (5.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

olaparib
paclitaxel
carboplatin
recurrent disease
cancer
Research Site
 (6.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

paclitaxel
kaposi sarcoma
non-small cell carcinoma
carboplatin
stage iia lung cancer ajcc v7
Neurosurgeons of New Jersey-Ridgewood
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +358 other locations
A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

systemic therapy
measurable disease
solid tumour
metastasis
oophorectomy
John Theurer Cancer Center at Hackensack University Medical Center
 (5.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma

The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy. The study will compare the effects of adding acupuncture to usual pain management with those of usual pain management alone, in reducing opioid use by …

high-dose chemotherapy
acupuncture
opioid use
pain management
opioid
Hackensack Meridian Health
 (5.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Double-Blind Multicenter Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19

This clinical trial will examine if a new treatment of Mesenchymal Stems Cells (called PLX-PAD) can help patients intubated and mechanically ventilated due to COVID-19 to recover more quickly with less complications.

covid-19
acute respiratory distress
SARS
respiratory distress
acute respiratory syndrome (sars)
Holy Medical Center
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Yoga for Anxiety in Adults

The purpose of this study is to investigate the effect of a telerehabilitation-yoga intervention delivered remotely via videoconferencing on adults with Parkinson's Disease and anxiety symptoms.

anxiety
parkinson's disease
anxiety symptoms
Rutgers University
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC). The study primary endpoints are …

ros1
systemic therapy
carboplatin
vitamin b12 level
stage iv non-small cell lung cancer
New Jersey Cancer Care and Blood Disorders (NJCCBD)
 (5.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +27 other locations