Bloomfield, New Jersey Clinical Trials

A listing of Bloomfield, New Jersey clinical trials actively recruiting patient volunteers.

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Found 44 clinical trials
Multi-center Open-label Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)

Primary Objectives: To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV) To evaluate the pharmacokinetics (PK) of SC and IV isatuximab Secondary Objectives: To estimate absolute bioavailability of SC and IV isatuximab To measure receptor occupancy (RO) after isatuximab SC versus IV administration To assess …

arginine hydrochloride
contraceptive use
hbv dna
lenalidomide
dexamethasone
Investigational Site Number 8400006
 (9.4 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +13 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

fitusiran
bethesda assay
haemophilia a
hemophilia
factor ix
Investigational Site Number 8400008
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Yoga for Anxiety in Adults

The purpose of this study is to investigate the effect of a telerehabilitation-yoga intervention delivered remotely via videoconferencing on adults with Parkinson's Disease and anxiety symptoms.

anxiety symptoms
anxiety
parkinson's disease
Rutgers University
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

This phase II trial compares high-dose rate brachytherapy and stereotactic ablative radiotherapy as monotherapy in treating patients with prostate cancer that has not spread to other parts of the body (localized). High-dose rate brachytherapy delivers radiation directly into the prostate within a few minutes by a single radioactive seed through …

adenocarcinoma
stage iia prostate cancer ajcc v8
treatment regimen
transrectal ultrasound
alpha blocker
Rutgers New Jersey Medical School
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC). The study primary endpoints are …

liquid biopsy
adjuvant therapy
BRAF
ros1
pemetrexed
New Jersey Cancer Care and Blood Disorders (NJCCBD)
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +27 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

drug test
epidermal growth factor
epidermal growth factor receptor
solid tumor
metastatic nsclc
Hackensack Univ Med Ctr /ID# 216484
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

bilateral oophorectomy
solid tumour
measurable disease
hysterectomy
oophorectomy
John Theurer Cancer Center at Hackensack University Medical Center
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma

The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy. The study will compare the effects of adding acupuncture to usual pain management with those of usual pain management alone, in reducing opioid use by …

lymphoma
pain management
multiple myeloma
high dose chemotherapy
opioid use
Hackensack Meridian Health
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

gaucher disease
eliglustat
imiglucerase
deficiency
Investigational Site Number 840057
 (6.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840057
 (6.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +135 other locations