Raleigh-Durham, North Carolina Clinical Trials

A listing of Raleigh-Durham, North Carolina clinical trials actively recruiting patient volunteers.

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Found 48 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
dulaglutide
cardiovascular disease
Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
None

Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
A Randomized Controlled Trial Assessing the Safety and Feasibility of Respiratory Muscle Training and Exercise Training in Children and Adolescents With Persistent Asthma  

The purpose of this study is to assess the safety and tolerability of a 6-week Inspiratory Muscle Training and cardiovascular exercise training program in children and adolescents with asthma. To also determine the efficacy of inspiratory muscle training and exercise in increasing respiratory muscle strength and endurance, and to explore …

dyspnea
persistent asthma
breathing exercises
Duke University
 (8.3 away)
  • 0 views
  • 20 Sep, 2024
  • 1 location
Expanded Access of Omidubicel for Allogeneic Transplantation in Patients With Hematological Malignancies

Omidubicel is an investigational therapy for patients with high-risk hematologic malignancies.

cancer
investigational treatment
hematologic malignancy
allogeneic transplantation
Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

antiandrogen therapy
androgen suppression
androgens
gonadorelin
bilateral orchidectomy
Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

cancer
proctoscopy
rectal cancer
adenocarcinoma
adenocarcinoma of rectum
Duke Cancer Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
None

Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 May, 2025
  • +12 other locations
None

Duke University Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 May, 2025
  • +13 other locations
Project HOPE 1000: Outcomes Related to Pregnancy

The purpose of this study is to collect biological samples from pregnant women and their babies and to collect data on long-term health, school outcomes, and the use of state and county services. The information we learn by doing this study may help identify important factors that may influence the …

Duke affiliated ObGyn clinics within Duke Health
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

gaucher disease
eliglustat
deficiency
imiglucerase
Investigational Site Number 840037
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations