Chapel Hill, North Carolina Clinical Trials

A listing of Chapel Hill, North Carolina clinical trials actively recruiting patient volunteers.

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Found 65 clinical trials
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

migraine
lasmiditan
preventive medication
ly573144
headache
University of North Carolina School of Medicine - Children's Hospital - Children's Research Institute
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

antiandrogen therapy
cancer
darolutamide
hormone therapy
abiraterone
Duke University Medical Center
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

adenocarcinoma of rectum
cancer
rectal cancer
adenocarcinoma
proctoscopy
Duke Cancer Center
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
None

Duke University Medical Center
 (8.0 away) Contact site
  • 0 views
  • 19 May, 2025
  • +12 other locations
None

Duke University Medical Center
 (8.0 away) Contact site
  • 0 views
  • 19 May, 2025
  • +13 other locations
A Randomized Controlled Trial Assessing the Safety and Feasibility of Respiratory Muscle Training and Exercise Training in Children and Adolescents With Persistent Asthma  

The purpose of this study is to assess the safety and tolerability of a 6-week Inspiratory Muscle Training and cardiovascular exercise training program in children and adolescents with asthma. To also determine the efficacy of inspiratory muscle training and exercise in increasing respiratory muscle strength and endurance, and to explore …

persistent asthma
breathing exercises
dyspnea
Duke University
 (8.0 away)
  • 0 views
  • 20 Sep, 2024
  • 1 location
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System - INFINITE-US

Prospective, non-randomized, multicenter pre-market early feasibility study (EFS) to evaluate subjects treated with the BlueLeaf System for the treatment of symptomatic CVI of the lower extremity

University of North Carolina at Chapel Hill
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Respiratory Muscle Training (RMT) in ALS

Twelve adults with ALS will participate in a study involving four 3-week cycles of progressive respiratory muscle training (RMT). The investigators will measure maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) weekly. The investigators will obtain the majority of measurements of MIP and MEP during web-based telehealth visits. Participants …

weakness
maximum expiratory pressure
maximum inspiratory pressure
respiratory muscle training
Duke University Medical Center
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Expanded Access of Omidubicel for Allogeneic Transplantation in Patients With Hematological Malignancies

Omidubicel is an investigational therapy for patients with high-risk hematologic malignancies.

allogeneic transplantation
cancer
investigational treatment
hematologic malignancy
Duke University Medical Center
 (8.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

platelet count
antineoplastic
antineoplastic agents
hras gene
corticosteroids
UNC Lineberger Comprehensive Cancer Center
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations