Silver Spring, Maryland Clinical Trials
A listing of Silver Spring, Maryland clinical trials actively recruiting patient volunteers.
Found 97 clinical trials
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Background Metastasis is the spread of cancer from one organ to a nonadjacent organ. It causes 90% of cancer deaths. No treatment specifically prevents or reduces metastasis. Researchers hope a new drug can help. It stops cancer cells from growing and spreading further and possibly shrink cancer lesions in distant …
- 0 views
- 24 Nov, 2025
- 1 location
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination
This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.
- 0 views
- 19 Feb, 2024
- +9 other locations
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication
Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.
- 0 views
- 19 Feb, 2024
- +2 other locations
SPRINT Peripheral Nerve Stimulation for the Treatment of Back Pain
The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Electrical stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The SPRINT PNS …
- 0 views
- 19 Feb, 2024
- +1 other locations
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis
Background Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options. Objective To test if the dietary supplement nicotinamide riboside can improve immune system function in the blood and skin of people …
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- 19 Feb, 2024
- 1 location
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure
This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with PB2452 in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure. Approximately 200 patients will be enrolled at approximately 200 centers worldwide. Patients with reported …
- 0 views
- 19 Feb, 2024
- +5 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.
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- 19 Feb, 2024
- +16 other locations
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier …
- 0 views
- 19 Feb, 2024
- +1 other locations
PET Imaging of Cyclooxygenases in Dementia
Background About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain contributes to these diseases. Researchers want to find a better way to measure this inflammation. Objective To learn if two new radiolabeled drugs, [11C]PS13 …
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- 19 Feb, 2024
- 1 location
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study
To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …
- 0 views
- 19 Feb, 2024
- +9 other locations