Durate, Illinois Clinical Trials

A listing of Durate, Illinois clinical trials actively recruiting patient volunteers.

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Found 64 clinical trials
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

pembrolizumab
anaplastic lymphoma
lung cancer
non-small cell lung cancer
venetoclax
Rush University Medical Center /ID# 212448
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

cataract
neutrophil count
crizotinib
measurable disease
neurofibroma
Lurie Children's Hospital of Chicago (Site 350)
 (7.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +16 other locations
Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke

A single-site, interventional, single-arm trial to evaluate the safety and efficacy on functional mobility following Samsung GEMS-H (Gait Enhancing and Motivating System - Hip) device training in participants with sub-acute and chronic stroke.

chronic stroke
mini-mental state examination
stroke
chronic cerebrovascular accident
Shirley Ryan AbilityLab
 (7.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

deficiency
gaucher disease
imiglucerase
eliglustat
Investigational Site Number 840079
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840011
 (7.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +135 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

glycogen storage disease type ii
myozyme
deficiency
replacement therapy
gaa gene
Investigational Site Number 840079
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +190 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

agalsidase beta
fabrazyme
deficiency
replacement therapy
alpha-galactosidase
Investigational Site Number 840079
 (4.1 away) Contact site
  • 0 views
  • 05 Aug, 2024
  • +136 other locations
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

bradykinesia
muscle rigidity
datscan
modafinil
methyldopa
Northwestern University
 (7.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +45 other locations
Clinical and Genetic Analysis of ROP

Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world. The investigators feel …

premature birth
pediatric
genetic analysis
blindness
vascular disease
University of Illinois Chicago
 (6.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The way the immune system responds to certain PD-related proteins in PD donors compared to the way it responds in persons without or fewer PD related proteins is not well studied and this study aims to analyze the autoimmune response in each group. The study involves a one time visit …

bradykinesia
muscle rigidity
parkinson's disease
tremor
resting tremor
Shirley Ryan Ability Lab
 (7.1 away)
  • 1784 views
  • 19 Feb, 2024
  • +2 other locations