Hamden, Connecticut Clinical Trials

A listing of Hamden, Connecticut clinical trials actively recruiting patient volunteers.

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Found 57 clinical trials
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

renal function
polycystic kidney disease
chronic kidney disease
depression
autosomal dominant
Investigational Site Number 8400010
 (3.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +80 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

Yale University Site Number : 8400081
 (4.6 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
Treatment of Pregnant Women With OUD

The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)

Yale New Haven Hospital Maternal Fetal Medicine Unit
 (2.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +11 other locations
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

Yale University School of Medicine
 (2.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose Escalation Study of PF-07209326 in Healthy Participants

This Phase 1 first-in-human single ascending dose and multiple dose study will be a randomized, double-blind, placebo-controlled investigation of the safety, tolerability, and pharmacokinetics of PF-07209326.

New Haven Clinical Research Unit
 (2.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

diabetes
type 1 diabetes mellitus
teplizumab
Clinical Site
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
A Study of LAM-002A for the Prevention of Progression of COVID-19

This is a clinical trial to evaluate the efficacy of LAM-002A compared to placebo treatment in adults with a confirmed SARS-CoV-2 infection who are receiving standards supportive care in an outpatient setting.

Yale University
 (3.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)

The study will evaluate the efficacy and safety of aprepitant injectable emulsion added to standard of care for hospitalized patients with COVID-19.

pulse oximetry
acute respiratory syndrome (sars)
SARS
PCR test
mechanical ventilation
Yale University School of Medicine
 (3.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
dulaglutide
tirzepatide
CMR of Greater New Haven, LLC
 (1.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carboplatin
endometrial cancer
recurrent disease
recurrent endometrial cancer
paclitaxel
Research Site
 (3.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations