San Dimas, California Clinical Trials

A listing of San Dimas, California clinical trials actively recruiting patient volunteers.

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Found 48 clinical trials
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

kras g12c mutation
metastatic malignant solid tumor
ki-ras
solid tumour
solid tumor
City of Hope Comprehensive Cancer Center
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +7 other locations
First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Primary Objective: To determine the maximum tolerated dose (MTD) of SAR442257 administered as a single agent in patients with relapsed and refractory multiple myeloma (RRMM) and refractory non-Hodgkin lymphoma (RR-NHL), and determine the recommended Phase 2 dose (RP2D) Secondary Objectives: To characterize the safety profile of SAR442257 To characterize the …

follicular lymphoma
diffuse large b-cell lymphoma
cancer treatment
cancer
chronic lymphocytic leukemia
Investigational Site Number 8400001
 (8.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

daratumumab
carfilzomib
bortezomib
ixazomib
refractory multiple myeloma
Investigational Site Number 8400002
 (8.5 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +7 other locations
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to three dose levels in adult participants aged 18 to 45 years with moderate to severe acne. This trial will consist of a …

Empire Clinical Research - Pomona- Site Number : 8400055
 (4.0 away) Contact site
  • 0 views
  • 29 Nov, 2025
  • +30 other locations
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

renal cell carcinoma
carcinoma
karnofsky performance status
Research Site 2
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors. Survivor self-management program focuses on coaching patients on follow-up care after cancer treatments. Participating in the program may improve knowledge and …

stage iia lung cancer ajcc v8
non-small cell lung cancer
lung cancer
cancer
stage i lung cancer ajcc v8
City of Hope Medical Center
 (10.0 away) Contact site
  • 4 views
  • 19 Feb, 2024
  • 1 location
Remotivation Process for Improving Adherence to Lymphedema Treatment Programs in Patients With Breast Cancer-Related Lymphedema

This trial studies how well the Remotivation Process in an occupational therapy program works in improving adherence to lymphedema treatment programs in patients with breast cancer-related lymphedema. Lymphedema treatment programs are well developed and effective, but adherence to these programs are an issue. The Remotivation Process is a series of …

lymphedema
breast cancer
breast carcinoma
cancer
carcinoma
City of Hope Medical Center
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

fluoropyrimidine
EGFR
metastatic colorectal cancer
monoclonal antibodies
solid tumour
City of Hope
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations