La Jolla,, California Clinical Trials

A listing of La Jolla,, California clinical trials actively recruiting patient volunteers.

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Found 62 clinical trials
Octagam 10% Therapy in COVID-19 Patients With Severe Disease Progression

This is a randomized, double-blind, placebo-controlled, multicenter, Phase 3 study to evaluate if high-dose Octagam 10% therapy can stabilize or improve clinical status in patients with severe Coronavirus disease

coronavirus infection
fraction of inspired oxygen (fio2)
covid-19
throat
chest imaging
Octapharma Research Site
 (8.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
coma
induced hypothermia
cardiac arrest
life support
UC San Diego Medical Center - Hillcrest
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
tirzepatide
dulaglutide
UCSD Clinical & Translational Research Institute
 (0.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

cancer therapy
measurable disease
durvalumab
endometrial cancer
cancer treatment
Research Site
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
positron emission tomography
alzheimer's disease
florbetapir
mini-mental state examination
Sharp Mesa Vista Hospital
 (8.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

pick's disease
dementia
aphasia
progranulin
University of California San Diego
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
treatment regimen
ly573144
migraine
preventive medication
Medical Center for Clinical Research
 (8.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants  

Primary Objective: To assess the safety profile of each SP0202 formulation and Prevnar 13 in toddlers and infants (after each and any injection). To assess the immune response (serotype specific IgG concentration) of the SP0202 formulations and Prevnar 13 1 month after the administration of one dose in toddlers (Groups …

Investigational Site Number 8400052
 (8.2 away)
  • 0 views
  • 19 Feb, 2024
  • +31 other locations
Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age

The primary objective of the study is to compare the clinical efficacy of high-dose quadrivalent influenza vaccine (QIV-HD) to standard-dose quadrivalent influenza vaccine (QIV-SD) in participants 6 months through 35 months of age for the prevention of laboratory-confirmed influenza illness caused by any influenza A or B type. The secondary …

quadrivalent inactivated influenza vaccine
influenza
hemagglutination inhibition
flu symptoms
vaccination
Investigational Site Number 8400008
 (8.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.

carcinoma
hepatocellular carcinoma
cirrhosis
University of California, San Diego
 (0.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location