Buena Park, California Clinical Trials

A listing of Buena Park, California clinical trials actively recruiting patient volunteers.

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Found 46 clinical trials
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

This is a Phase 3, multi-center, randomized, open-label, controlled study designed to evaluate the safety and efficacy of cabozantinib given in combination with atezolizumab versus a second novel hormonal therapy (NHT) in men with metastatic castration-resistant prostate cancer (mCRPC) who have previously been treated with one, and only one, NHT …

prostate adenocarcinoma
enzalutamide
testosterone
bone disease
endocrine therapy
Exelixis Clinical Site #2
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
tirzepatide
dulaglutide
Diabetes Associates Medical Group
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to three dose levels in adult participants aged 18 to 45 years with moderate to severe acne. This trial will consist of a …

Core Healthcare Group- Site Number : 8400067
 (3.5 away) Contact site
  • 0 views
  • 29 Nov, 2025
  • +30 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

testosterone
measurable disease
enzalutamide
cancer
combination therapy
The Oncology Institute of Hope & Innovation
 (5.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

measurable disease
drug test
metastatic nsclc
small cell lung cancer
anaplastic lymphoma
Icri /Id# 217071
 (5.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Patient-Derived Xenografts to Reduce Cancer Health Disparities

This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.

biospecimen collection
lung cancer
gastric cancer
bladder cancer
liver cancer
UC Irvine Health/Chao Family Comprehensive Cancer Center
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations