Azusa, California Clinical Trials

A listing of Azusa, California clinical trials actively recruiting patient volunteers.

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Found 45 clinical trials
Multi-center Open-label Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)

Primary Objectives: To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV) To evaluate the pharmacokinetics (PK) of SC and IV isatuximab Secondary Objectives: To estimate absolute bioavailability of SC and IV isatuximab To measure receptor occupancy (RO) after isatuximab SC versus IV administration To assess …

parenteral administration
arginine
measurable disease
tuberculosis
refractory multiple myeloma
Investigational Site Number 8400002
 (2.6 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +13 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

tirzepatide
cardiovascular disease
dulaglutide
body mass index
Valley Clinical Trials, Inc.
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Primary Objective: To determine the maximum tolerated dose (MTD) of SAR442257 administered as a single agent in patients with relapsed and refractory multiple myeloma (RRMM) and refractory non-Hodgkin lymphoma (RR-NHL), and determine the recommended Phase 2 dose (RP2D) Secondary Objectives: To characterize the safety profile of SAR442257 To characterize the …

cancer therapy
measurable disease
ct scan
recurrent disease
follicular lymphoma
Investigational Site Number 8400001
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

cell transplantation
measurable disease
thalidomide
autologous hematopoietic stem cell transplant
refractory multiple myeloma
Investigational Site Number 8400002
 (2.6 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +7 other locations
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

karnofsky performance status
renal cell carcinoma
carcinoma
Research Site 2
 (4.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors. Survivor self-management program focuses on coaching patients on follow-up care after cancer treatments. Participating in the program may improve knowledge and …

cancer therapy
stage iiic lung cancer ajcc v8
small cell lung cancer
stage iiic colorectal cancer ajcc v8
stage iii colorectal cancer ajcc v8
City of Hope Medical Center
 (4.0 away) Contact site
  • 4 views
  • 19 Feb, 2024
  • 1 location
Follow-up Study of Growth Safety and Efficacy of an Infant Formula for Healthy Term Infants

The purpose of this two-month follow-up study is to continue to follow growth, safety, and other health outcomes of infants fed a new infant formula for term infants or comparator formula. A reference group of human milk-fed infants will also be followed. This study is designed in accordance with Good …

San Gabriel Women's Health
 (8.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +24 other locations
Remotivation Process for Improving Adherence to Lymphedema Treatment Programs in Patients With Breast Cancer-Related Lymphedema

This trial studies how well the Remotivation Process in an occupational therapy program works in improving adherence to lymphedema treatment programs in patients with breast cancer-related lymphedema. Lymphedema treatment programs are well developed and effective, but adherence to these programs are an issue. The Remotivation Process is a series of …

cancer
lymphedema
carcinoma
breast carcinoma
breast cancer
City of Hope Medical Center
 (4.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

combination therapy
irinotecan
antibody therapy
measurable disease
fluoropyrimidine
City of Hope
 (4.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

This phase I trial studies the side effects and best dose of chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain in treating patients with MPP2+ glioblastoma that has come back (recurrent) or that is growing, spreading, or getting worse (progressive). Vaccines made from a gene-modified virus may …

expression by immunohistochemistry
tumor cells
measurable disease
leukapheresis
recurrent disease
City of Hope Medical Center
 (4.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location