Scarborough, Canada Clinical Trials

A listing of Scarborough, Canada clinical trials actively recruiting patients volunteers.

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Found 42 clinical trials
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

breast cancer staging
potassium
advanced breast cancer
carcinoma
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

lymphadenopathy
cancer
external beam radiotherapy
squamous cell carcinoma
carcinoma
Gregory J Czarnota
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease

This clinical trial focus on the delivery of Cerezyme in Parkinson's Disease (PD) patients using MR-guided focused ultrasound (MRgFUS) induced opening of the blood-brain barrier (BBB).

parkinson's disease
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 16 views
  • 19 Feb, 2024
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
dulaglutide
cardiovascular disease
LMC Endocrinology Centres Ltd.
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

postoperative cognitive dysfunction
memory impairment
comatose
coma
cognitive impairment
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
flortaucipir
florbetapir
mini-mental state examination
alzheimer's disease
Toronto Memory Program
 (6.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
None

Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

adenocarcinoma of prostate
adenocarcinoma
stereotactic body radiation therapy
Sunnybrook Health Sciences Center
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prone Positioning for Patients on General Medical Wards With COVID19

COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone. Randomization will be stratified by site.

fraction of inspired oxygen (fio2)
nosocomial infection
covid-19
mechanical ventilation
FIO2
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

measurable disease
head and neck carcinoma
cancer
carcinoma
neck cancer
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location