Outremont, Canada Clinical Trials

A listing of Outremont, Canada clinical trials actively recruiting patients volunteers.

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Found 51 clinical trials
Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty

The purpose of this study is to compare infection rates when patients, elected for primary or aseptic revision THA / TKA, have a single intravenous antibiotic dose versus one single intravenous antibiotic dose in combination with intra-articular antibiotics. This is a prospective, randomized clinical survey on selected outcome measurements on …

vancomycin
osteonecrosis
antibiotic therapy
total knee replacement
antibiotics
Hopital Sacr -Coeur de Montreal
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

docetaxel
immune checkpoint inhibitor
non-squamous non-small cell lung cancer
squamous non-small cell lung cancer
squamous nsclc (non-small cell lung cancer)
Investigational Site Number 1240004
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +168 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

pregnancy test urine
contraceptive use
urine test
aubagio
brain lesion
Investigational Site Number 1240005
 (7.2 away) Contact site
  • 0 views
  • 09 Sep, 2025
  • +24 other locations
An Open-label Ascending Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 2-17 years with Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) in order to identify the dose and regimen for adequate treatment of this population Secondary Objective: To describe the pharmacodynamic (PD) profile, the efficacy and the long-term safety of …

rheumatoid factor
disease modifying antirheumatic drugs
anti-rheumatic drugs
sarilumab
arthritis
Investigational Site Number 1240112
 (1.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +33 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
dulaglutide
body mass index
tirzepatide
Clinique Sant Cardio MC
 (4.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

olaparib
paclitaxel
carboplatin
recurrent disease
cancer
Research Site
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
positron emission tomography
florbetapir
flortaucipir
mini-mental state examination
Clinique Neuro Rive-Sud
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

antiandrogen therapy
prostatic neoplasm
testosterone
enzalutamide
taxane
Centre hospitalier de l'Universit de Montr al (CHUM) Centre de Recherche
 (2.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease. T2D and heart disease share many common risk factors such as aging, obesity and unhealthy lifestyle. Paradoxically however, while lowering blood LDL, commonly known as "bad cholesterol", …

omega-3 fatty acids
heart disease
body mass index
diabetes
fatty acids
Montreal Clinical Research Institute
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

vaccination
riluzole
ravulizumab
edaravone
Montreal Neurological Institute and Hospital
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations