a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1927 clinical trials
The Effect of Time-Restricted Eating in Cardiometabolic Health

However, an understanding of the effect of TRE on cardiometabolic health in people is not clear and few studies have evaluated this issue. Accordingly, the investigators propose to conduct a randomized controlled trial in people with obesity and prediabetes to determine the effect of 9 h TRE for 12 weeks, …

fasting
insulin
glucose intolerance
cardiovascular disease
hemoglobin a1c
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

This is a prospective, single-center, open-label, single-dose, Phase 1 study, to assess the effect of moderate hepatic impairment due to liver cirrhosis on the pharmacokinetics of aprocitentan (ACT-132577).

systolic blood pressure
follicle stimulating hormone
renal function
moderate hepatic insufficiency
bilateral salpingectomy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

cisplatin
cancer
carcinoma
concomitant radiochemotherapy
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluating the Clinical Value of Traditional Chinese Medicine in the Adjuvant Therapy of Triple-negative Breast Cancer

This is a prospective, single site, randomized, double-blind Phase III clinical trial to evaluate the clinical value of Traditional Chinese Medicine in the adjuvant therapy of triple-negative breast cancer patients.

HER2
cancer
triple negative breast cancer
epidermal growth factor receptor
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostatic neoplasms, castration-resistant
cancer
combined modality therapy
combination therapy
testosterone
  • 0 views
  • 19 Feb, 2024
  • 22 locations
Wearable Monitoring Systems for Swallowing Function and Disorders

Wearable tele-rehabilitation technology allows for the efficient provision of rehabilitation services from a distance, facilitating tele-management of many disorders. The proposed research will develop and validate a set of mechanically compliant, easy-to-use, and inexpensive wearable tele-monitoring systems, for future use in the rehabilitation of swallowing disorders (dysphagia).

dysphagia
stroke
parkinson's disease
neurological disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized Imaging for New Treatments

Magnetic resonance imaging (MRI) has the advantage of being a radiation-free modality, making it more suitable for assessing response to therapy in a shorter time frame with repeated imaging.

cystic fibrosis
multiple breath washout
antibiotic therapy
sweat test
antibiotics
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Multi Neuro-functional Biomarkers for Monitoring the Effects of Treatments in ADHD Children

ADHD group is evaluated before the beginning of medications, at first dose of medication (only imaging evaluation fNIRS), and after a period of two/three months of continuous treatment with medication.

attention deficit disorder
methylphenidate
psychiatric disorders
deficit
attention deficit hyperactivity disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

These will be from both lesions and unaffected areas. The areas will be injected with a numbing medicine. A round cutting device will remove small pieces of skin from each area. Participants will take the study supplement or a placebo starting at the first visit.

niacin
nicotinamide
psoriasis
urine test
chronic inflammation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Minocycline in MS: Confirmation of Benefit

Treatment with minocycline until the endpoint is reached or to a maximum of 24 months or until the last-enrolled participant reaches their 12 month visit.

demyelinating disorder
oligoclonal bands
multiple symptoms
brain lesion
MRI
  • 0 views
  • 19 Feb, 2024
  • 1 location