a, a N Clinical Trials
A listing of a, a N clinical trials actively recruiting patients volunteers.
Found 1927 clinical trials
OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)
OTL-200 is a cryopreserved dispersion for infusion containing autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene.
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- 19 Feb, 2024
- 1 location
Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis
Subjects enrolled in the standard of care group will receive a voucher to Weight Watchers after study completion.
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- 19 Feb, 2024
- 1 location
Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease
To investigate the safety and efficacy of an orally administered dose of TW-012R in patients with Alzheimer's disease bearing PSEN1 (presenilin 1) mutations (PSEN1-AD), using a placebo group as a control. In addition, long-term safety will be examined in an open-label extension trial.
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- 19 Feb, 2024
- 7 locations
Effectiveness of Oral Health Promotion in Bottle Fed Children
Half of the patient will receive oral health promotion which emphasizing more on the benefit of stopping the bottle feeding habit, a free-flow cup and oral hygiene kit which include a toothbrush, toothpaste (1000ppm fluoride). The other half of the patient will receive standard of care oral hygiene promotion and …
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- 19 Feb, 2024
- 1 location
Personalized Extended Interval Dosing of Natalizumab in Relapsing Remitting Multiple Sclerosis
This leads to fewer hospital visits, a decrease of healthcare costs and decrease of risk of complications of natalizumab treatment. Objective: The objective is to test feasibility and validate safety of personalized extended interval dosing of natalizumab in a large real-life cohort across the Netherlands.
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- 19 Feb, 2024
- 15 locations
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor
This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine …
- 0 views
- 19 Feb, 2024
- 1 location
Using PRP and Cord Blood in Treatment of Covid -19
covid - 19 is a critical viral infection that affects humans
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- 19 Feb, 2024
- 1 location
Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer
Camrelizumab (SHR-1210) is a humanized anti-PD1 IgG4 monoclonal antibody.
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- 19 Feb, 2024
- 1 location
Multi-CAR-T Cells Targeting B Cell Lymphomas
Clinical response and development of a simplified and standardized lentiviral vector and cell production protocol will be investigated. This is a phase I/II trial enrolling patients from multiple clinical centers.
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- 19 Feb, 2024
- 3 locations
Prone Positioning for Patients on General Medical Wards With COVID19
COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone.
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- 19 Feb, 2024
- 7 locations