a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1927 clinical trials
A Clinical Trail of Traditional Chinese Medicine Rehabilitation for Stroke Lead to Dysphagia / Cognitive Disorder

The traditional Chinese medicine rehabilitation for the deglutition and cognitive impairment after stroke will be intervened, which can promote the recovery of dysphagia and cognitive function of stroke patients, reduce the disability rate and improve the quality of life.

cerebral infarction
ischemic stroke
dysphagia
acupuncture
infarct
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Trial Evaluating the Efficacy of Metastasectomy in Patients With Oligo-Metastatic Breast Cancer(OMIT)

This is a randomized clinical trial (OMIT study) evaluating the efficacy of metastasectomy in patients with oligo-metastatic breast cancer.

metastasis
measurable disease
stage iv breast cancer
liver metastasis
kidney function tests
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Randomized Multi-institutional Study of Sodium Thiosulfate as Auditory Protection for Children With Hepatoblastoma

A Phase 3 multi-institutional study for treatment of children with newly diagnosed hepatoblastoma using a modified Paediatric Hepatic International Tumour Trial (PHITT) strategy incorporating a randomized assessment of sodium thiosulfate as auditory protection for children with localized disease, and response adapted therapy for patients with metastatic disease

pulmonary function tests
renal function
cancer
glomerular filtration rate
metastatic disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

This is an open label Phase 1, First in Human trial of TST001, a recombinant humanized anti-Claudin 18.2 (CLDN18.2) IgG1 monoclonal antibody. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic, colon and lung cancers.

lung cancer
measurable disease
solid tumor
hair thinning
solid neoplasm
  • 0 views
  • 19 Feb, 2024
  • 1 location
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma

The proposed study is a two-step trial with 1) a safety run in part conducted in pediatric patients and 2) a Phase II part in adult and pediatric patients aiming to evaluate the safety and clinical activity of atezolizumab + cobimetinib in advanced/metastatic soft tissue sarcomas.

mek inhibitor
measurable disease
total serum bilirubin
pediatric
hair thinning
  • 0 views
  • 19 Feb, 2024
  • 4 locations
A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base

Randomized comparison between Platelet Rich Plasma (PRP) and placebo (Saline) for thumb base.osteoarthritis.

arthritis
osteoarthritis
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Test How Well Healthy Men and Women Tolerate Different Doses of BI 706321

The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 706321 in healthy male and female subjects following oral administration of multiple rising doses for 14 days.

12 lead ECG
interferon gamma release assay
estradiol
male contraception
absolute neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

  • 0 views
  • 19 Feb, 2024
  • 10 locations
A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib

REMD-477 is a human anti-glucagon receptor antibody. Its proposed mechanism of action in controlling hyperglycemia is by blocking glucagon receptor (GCGR) signaling.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Immunogenicity Study of GX-19 a COVID-19 Preventive DNA Vaccine in Healthy Adults

The objective of our study is to evaluate safety, tolerability, and immunogenicity of COVID-19 preventive DNA vaccine in healthy volunteers.

body mass index
dna vaccine
covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location