a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1890 clinical trials
A Study of Two Formulations of Ixekizumab in Healthy Participants

The purpose of this study is to compare two different formulations of ixekizumab. One formulation (Reference) is approved by the Food and Drug Administration (FDA) and one formulation (Test) is not approved. This study will compare how much of each formulation gets into the blood stream. Information about any side …

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  • 19 Feb, 2024
A Trial of ZL-1201 in Subjects With Advanced Cancer

First in Human, Phase I Trial of Anti-CD47 Antibody ZL-1201 in Subjects with Advanced Cancer

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  • 19 Feb, 2024
A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor

This study is an open-label, multicenter, phase I/II study to evaluate the safety, PK and clinical efficacy of avapritinib in Chinese subjects with unresectable or metastatic GIST. The study consists of two parts: dose escalation (phase I) and dose expansion (phase II).

kinase inhibitor
gastrointestinal stromal tumor
adjuvant
imatinib
blu-285
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  • 19 Feb, 2024
Effects of Feedback on Learning of a Motor Sequence Task

This project will study how the feedback that is provided during practice of a movement skill can help people learn and build confidence. The investigators will measure motor skill performance and confidence before and after a session of motor practice.

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  • 19 Feb, 2024
Correlation of VEGF-A and Fluid Balance in Septic Shock

VEGF is a key molecule in the control of vascular permeability via interactions with the VEGF-receptor on the endothelial cell. Several authors reported plasma VEGF levels are elevated in sepsis shock and associated with increased mortality (1,2).

vasoconstrictor
antibiotics
administration of intravenous fluids
shock
vascular endothelial growth factor
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  • 19 Feb, 2024
Effects of Brain Stimulation on Cognition Oscillations and GABA Levels in Schizophrenia

The purpose of this study is to use a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), to test a set of hypotheses about the role of the prefrontal cortex in behavioral and neural correlates of cognition in schizophrenia.

schizophrenia
task performance
brain stimulation
clozapine
transcranial direct current stimulation
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  • 19 Feb, 2024
A Trial of Traffic Light Labeling With Behavioral Nudges and a Healthy Recipe Database to Increase Selection of Healthier Foods in Client-choice Food Pantries

This study is a pilot evaluation of the Healthy Pantry Program, a new behavioral economics-based training that allows pantry staff to learn how to implement nudges integrating traffic-light nutrition labeling and a healthy recipe database in the pantry environment.

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  • 19 Feb, 2024
Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm

Half of the subjects will receive transdermal flumazenil for 7-10 days, and half will receive a placebo. [11C]Flumazenil GABA-A receptor PET imaging will be used to assess target engagement effects.

serum pregnancy test
brain imaging
parkinson's disease
anxiety
cholinesterase inhibitors
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  • 19 Feb, 2024
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency

This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.

eruption
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  • 19 Feb, 2024
A Study of ICP-022 in Patients With R/R DLBCL

It is a phase II, multicenter, open-label study is to evaluate the safety, efficacy and pharmacokinetics of a novel BTK inhibitor, ICP-022, in approximately 85 subjects with R/R DLBCL.

lymphoma
large b-cell lymphoma
b-cell lymphoma
btk inhibitor
diffuse large b-cell lymphoma
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  • 19 Feb, 2024