a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1863 clinical trials
Prone Positioning for Patients on General Medical Wards With COVID19

COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone.

nosocomial infection
covid-19
fraction of inspired oxygen (fio2)
mechanical ventilation
FIO2
  • 0 views
  • 19 Feb, 2024
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine …

nephrectomy
kidney tumor
renal neoplasm
hyperpolarized carbon c 13 pyruvate
aggressiveness
  • 0 views
  • 19 Feb, 2024
Multi-CAR-T Cells Targeting B Cell Lymphomas

Clinical response and development of a simplified and standardized lentiviral vector and cell production protocol will be investigated. This is a phase I/II trial enrolling patients from multiple clinical centers.

  • 0 views
  • 19 Feb, 2024
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2

Investigational Drug Sub-study A: Brigatinib

glioma
bilateral tubal ligation
investigational therapy
meningiomatosis
experimental therapy
  • 0 views
  • 19 Feb, 2024
Adductor Canal Block (ACB) Versus ACB /Saphenous Block in Patients Undergoing Anterior Cruciate Ligament Repair

It carries potential benefits that encourage anesthesiologists to do it. It has a motor sparing property. Injection of local anesthetics in this lengthy canal that contains a variable amount of connective or fibrous tissue might lead to a patchy distribution of local anesthetics.

anesthesia
analgesia
bupivacaine
local anesthetics
anaesthesia
  • 0 views
  • 19 Feb, 2024
Enzalutamide Treatment in COVID-19

COVID-19 is a disease with high rate of morbidity if symptomatic. There is a great need of treatments to decrease the severity. The vast majority of patients needing intensive care are men, and this may be due to the androgens, either by regulation of TMPRSS2, necessary for virus internalization, or …

enzalutamide
oral contraceptives
covid-19
  • 0 views
  • 19 Feb, 2024
Longitudinal Immune-phenotyping of HCC Following MK-3475

The study comprises a main study of pembro-treated HCC patients and a sub-study of untreated HCC patients. In the main study, patients will be treated with pembrolizumab as neoadjuvant treatment approximately 4 weeks prior scheduled surgery.

hepatocellular carcinoma
serum pregnancy test
anticoagulants
immunomodulator
oncolytic virus therapy
  • 0 views
  • 19 Feb, 2024
Dynamically Tailored Behavioral Interventions in Diabetes

This study is a two-arm randomized controlled trial with n=280 participants recruited from the participating Federally Qualified Health Centers (FQHCs).

behavior modification
self monitoring
  • 0 views
  • 19 Feb, 2024
Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia

The intervention group discontinues antibiotics at day 5 if clinically stable and afebrile. The control group receives antibiotics for a duration of 7 days or longer at the discretion of the treating physician. The primary outcome is 90-day survival without clinical or microbiological failure to treatment, which will be tested …

  • 0 views
  • 19 Feb, 2024
Early Use of Airway Pressure Release Ventilation (APRV) in ARDS

Airway pressure release ventilation (APRV) is a time-cycled, pressure controlled, intermittent mandatory ventilation mode with extreme inverse I:E ratios. Currently it is considered as a non-conventional ventilatory mode.

respiratory distress
acute respiratory distress
intermittent mandatory ventilation
fraction of inspired oxygen (fio2)
airway pressure release ventilation
  • 0 views
  • 19 Feb, 2024