a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1927 clinical trials
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

This study will thus explore and attempt to treat a new risk factor for T2D using an inexpensive and widely accessible nutraceutical, which would aid in preventing T2D in humans.

omega-3 fatty acids
insulin
insulin sensitivity/resistance
fish oil
fatty acids
  • 0 views
  • 19 Feb, 2024
  • 1 location
CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies

Building on previous in vitro studies that have shown successful production of CAR+ T-cells using a new production approach, the investigators are now studying the ability to produce these CAR+ T-cells and determine how well they work in the clinical setting.

ejection fraction
cancer
adult acute lymphocytic leukemia
apheresis
cns disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Determination Safety and Tolerability of Epigenetic and Immunomodulating Drugs in Combination With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer.

A multi-center, open-label phase I/II study to to determine the safety and tolerability of Azacitidine and/or Romidepsin in combination with nab-Paclitaxel/Gemcitabine in patients with advanced pancreatic ductal adenocarcinoma (PDAC) (Part 1), followed by sequential immune targeting with programmed death-ligand (PD-L)1 blockade in combination with low-dose Lenalidomide (Part 2) in patients …

antineoplastic agents
cancer
romidepsin
adenocarcinoma
pdac
  • 0 views
  • 19 Feb, 2024
  • 8 locations
Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

This pilot study is configured as a non-inferiority comparison of Performance Status 2 patients with Performance Status 0-1 patients, with the goal of demonstrating non-inferiority in terms of efficacy (progression-free survival, overall survival) and safety (rates of adverse events, quality of life) when treating Performance Status 2 patients with the …

cancer
carboplatin/paclitaxel
small cell lung cancer
pemetrexed
dyspnea
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation therapy to control soft tissue sarcoma after surgery.

soft tissue sarcoma
sarcoma of the extremity
primary tumor
serum pregnancy test
sarcoma
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Brain Ultrasound With Contrast Microbubbles Injection in Shock Status

Alterations in the brain microcirculation may be involved in patients with shock. For a three-day period, we investigate the brain microcirculation using contrast-enhanced ultrasound with microbubble injection in patients with septic and non-septic shock.Ultrasound examination is performed daily to estimate global cerebral blood flow, and to evaluate the brain microcirculation, …

refractory shock
oliguria
delirium
brain perfusion
lactic acid
  • 0 views
  • 19 Feb, 2024
  • 1 location
Improving Access to Abortion in the Republic of Georgia

In the Republic of Georgia, the medical abortion regimen involves three in-person visits. This study aims to pilot and evaluate a simplified medical abortion service delivery model that will reduce the number of in-person visits to only one visit for diagnosis and counseling.

medical abortion
mifepristone
abortion early
  • 0 views
  • 19 Feb, 2024
  • 3 locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

shortness of breath
aortic valve replacement
regurgitation
fatigue
  • 0 views
  • 19 Feb, 2024
  • 10 locations
ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation

All participants will be randomized to one of two groups: The first group receives direct access to the online self-help intervention and the second group is a waiting control group that receives access to the program 3 weeks later. In both conditions additional care or treatment is allowed.

covid-19
psychological stress
  • 0 views
  • 19 Feb, 2024
  • 1 location
MCB Vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT

The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear pathological diagnosis and should be removed unless there are significant complications. But currently, the diagnostic rate of EUS-FNA for upper gastrointestinal subcutaneous lesions is less than 60%.

  • 0 views
  • 07 May, 2025
  • 1 location