Markham, Canada Clinical Trials

A listing of Markham, Canada clinical trials actively recruiting patients volunteers.

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Found 39 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

tirzepatide
cardiovascular disease
dulaglutide
body mass index
LMC Endocrinology Centres Ltd.
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive deficits
cognitive deficit
coronary artery bypass graft
sternotomy
anesthetics
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
mini-mental state examination
alzheimer's disease
florbetapir
positron emission tomography
Toronto Memory Program
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
None

Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

stereotactic body radiation therapy
adenocarcinoma of prostate
adenocarcinoma
Sunnybrook Health Sciences Center
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prone Positioning for Patients on General Medical Wards With COVID19

COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone. Randomization will be stratified by site.

FIO2
nosocomial infection
mechanical ventilation
covid-19
fraction of inspired oxygen (fio2)
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

head and neck carcinoma
renal function test
measurable disease
photoacoustic imaging
neutrophil count
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

locally advanced breast cancer
breast neoplasm
HER2
breast mass
advanced breast cancer
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Sunnybrook Type 2 Diabetes Study

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from …

impaired glucose tolerance
type 2 diabetes mellitus
hemoglobin a1c
fasting
cardiac rehabilitation
Sunnybrook Research Institute
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location