Greenfield Park, Canada Clinical Trials

A listing of Greenfield Park, Canada clinical trials actively recruiting patients volunteers.

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Found 51 clinical trials
Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery Analgesia

This study is a Randomized Control Trial comparing the Erector Spinae Plane Block with intrathecal morphine for post cesarean delivery analgesia.

Royal Victoria Hospital
 (4.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

cancer
non-small cell lung cancer
squamous nsclc (non-small cell lung cancer)
lung cancer
docetaxel
Investigational Site Number 1240003
 (0.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +168 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

pregnancy test urine
teriflunomide
serum pregnancy test
brain lesion
aubagio
Investigational Site Number 1240005
 (0.7 away) Contact site
  • 0 views
  • 09 Sep, 2025
  • +24 other locations
An Open-label Ascending Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 2-17 years with Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) in order to identify the dose and regimen for adequate treatment of this population Secondary Objective: To describe the pharmacodynamic (PD) profile, the efficacy and the long-term safety of …

rheumatoid factor
anti-rheumatic drugs
disease modifying antirheumatic drugs
antirheumatic
sarilumab
Investigational Site Number 1240112
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +33 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
ViaCar Recherche Clinique
 (1.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

cancer therapy
maintenance therapy
cancer
immunomodulators
measurable disease
Research Site
 (7.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
alzheimer's disease
flortaucipir
positron emission tomography
mini-mental state examination
Clinique Neuro Rive-Sud
 (0.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

taxane
prostatic neoplasms, castration-resistant
antiandrogen therapy
cancer
antiandrogens
Centre hospitalier de l'Universit de Montr al (CHUM) Centre de Recherche
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease. T2D and heart disease share many common risk factors such as aging, obesity and unhealthy lifestyle. Paradoxically however, while lowering blood LDL, commonly known as "bad cholesterol", …

diabetes
body mass index
heart disease
omega-3 fatty acids
insulin
Montreal Clinical Research Institute
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

vaccination
riluzole
ravulizumab
edaravone
Montreal Neurological Institute and Hospital
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations