Vision Loss Clinical Trials

A listing of Vision Loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 292 clinical trials
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

ct scan
tas-102
colon cancer
adenocarcinoma
colorectal cancer
  • 0 views
  • 19 Feb, 2024
  • 37 locations
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation (TIRO-AF)

This is a single center randomized double blind controlled study of patients (BMI> 30 kg/m2) with obesity and Atrial Fibrillation (AFIB) randomized to Tirzepatide vs. placebo.

  • 0 views
  • 31 Jan, 2025
  • 1 location
Sciatic Nerve Block With ALX006 in Subjects Undergoing Bunionectomy

This is a Phase 2, randomized, double-blind, active-controlled, dose-escalation study evaluating the safety, pharmacokinetics, efficacy, and pharmacodynamics of ALX006, an extended-release bupivacaine formulation, administered as a single-dose sciatic nerve block in the popliteal fossa in adult subjects undergoing primary unilateral bunionectomy.

  • 0 views
  • 07 May, 2026
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC).

adjuvant
folic acid
systemic therapy
measurable disease
carboplatin
  • 0 views
  • 19 Feb, 2024
  • 28 locations
Prospective Evaluation of a Dose Guidance System for People With Diabetes Initiating Basal Insulin or Using Insulin Injections (DGS)  

A prospective, randomized, single blind, two-arms, multicenter study. The study aims to assess the safety of a dosing-guided system (DGS) that provides direct advice on insulin dosing recommendations and diabetes management to individuals with diabetes using insulin or starting basal insulin therapy, guided by their continuous glucose monitoring (CGM).

  • 0 views
  • 08 Dec, 2025
  • 1 location
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Objectives: To analyze adherence to physical rehabilitation by mobile App and to evaluate the effectiveness of lumbopelvic stability exercises performed at home with the App. Material and methods: Randomized controlled single blind pilot study (n = 30). Participants with Stroke (<6 months) will be randomized between two groups (App for …

hemiparesis
hemiplegia or hemiparesis
stroke
physical rehabilitation
hemiplegia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging

The investigators will use a dual-site, 12- week drug intervention trial performed in a double-blind, placebo-controlled manner on 148 subjects recruited from two separate sites (Oklahoma Medical Research Foundation (OMRF) and University of Illinois Urbana-Champaign (UIUC)).

insulin
muscle biopsy
chronic disease
a 12
diabetes
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Investigating the Effectiveness of Graded Motor Imagery Training in Children With Obstetric Brachial Plexus Injury

The aim of this study is to investigate the effect of graded motor imagery training on upper extremity motor function, proprioception, functional mobility, balance and quality of life in patients with obstetric brachial plexus injury in addition to conventional treatment. In this context, our aim is to identify new and …

  • 0 views
  • 12 May, 2025
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier …

  • 0 views
  • 19 Feb, 2024
  • 2 locations
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

This study is designed to investigate whether sympathoinhibition with moxonidine could provide added metabolic benefit compared to the second line therapy in the current guidelines.

ace inhibitor
amlodipine 5 mg
moxonidine
amlodipine
hypertension
  • 0 views
  • 19 Feb, 2024
  • 1 location