Lymphocytic Leukemia, Acute Clinical Trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 654 clinical trials
89Zr-atezolizumab PET Scan and Lobular Breast Cancer

Ten patients with lobular metastatic breast cancer, who are included in the GELATO trial at the UMCG, are eligible for the ImaGelato study. All patients will undergo two Zirconium-89 (89Zr)-atezolizumab positron emission tomography (PET) scans, one at baseline and one after two doses carboplatin induction treatment.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Benefits of Exercise in Alzheimer's Disease

Ultimately, the hope is that the results of this study could be used to facilitate exercise programs for patients. Enrollment is completely voluntary and all personal data obtained will remain confidential.

behavioral symptoms
dementia
cognitive assessment
neuropsychological test
aerobic exercise
  • 4 views
  • 19 Feb, 2024
  • 1 location
Immunity and Safety of Covid-19 Synthetic Minigene Vaccine

The infection of Covid-19 is mediated through binding of the Spike protein to the ACEII receptor, and the viral replication depends on molecular mechanisms of all of these viral proteins. This trial proposes to develop and test innovative Covid-19 minigenes engineered based on multiple viral genes, using an efficient lentiviral …

  • 0 views
  • 19 Feb, 2024
  • 3 locations
Phase 1/2 Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA (reiMMAgine)

All subjects will be monitored closely for safety for the first year of the study and then annually for an additional 4 years.

  • 0 views
  • 19 Feb, 2024
  • 1 location
CD19 CAR-T Expressing IL7 and CCL19 Combined With PD1 mAb for Relapsed or Refractory Diffuse Large B Cell Lymphoma

However, a large number of clinical studies have shown that about 20% of patients with B-ALL and 50% of patients with B-NHL cannot achieve complete remission (CR) after CD19-CAR-T treatment. Targeting tumor microenvironment is an important new method to overcome the drug resistance of CAR-T cells.

antibody therapy
b-cell acute lymphoblastic leukemia
remission
hodgkin's disease
flow cytometry
  • 0 views
  • 19 Feb, 2024
  • 1 location
Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment

Strong and constant overexpression of PDL1 and NK cells has been found in all subtypes and settings of GTN tumors from French reference gestational trophoblastic center. Complete and durable responses to pembrolizumab were reported in 3 patients with multi-chemoresistant GTN in United Kingdom.

  • 0 views
  • 19 Feb, 2024
  • 8 locations
Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT

The investigators propose a prospective, multicentre study of all cases of intrastent restenosis, examined by angiography, causing clinical features involving stable angina and acute coronary syndrome.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Participants will have visits 6 months. At 6 months, they will repeat all the screening tests and also have: Quality-of-life questionnaire Neurodevelopmental test (for participants younger than 18 years) If participants blood cell counts improve, they may keep taking eltrombopag for up to 3 more years.

bone marrow erythroid
bone marrow biopsy
cell counts
anemia
blood transfusion
  • 0 views
  • 19 Feb, 2024
  • 1 location
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

T lymphocytes can kill tumor cells but there normally are not enough of them to kill all the tumor cells. Some researchers have taken T cells from a person's blood, grown more of them in the laboratory and then given them back to the person.

cancer
aptt
pulse oximetry
apheresis
leukemia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide

Small cell lung cancer (SCLC) is a rapidly proliferating, neuroendocrine tumor that accounts for about 15% of all lung cancers. Most patients have metastases at primary diagnosis involving sites like bone, adrenal glands, liver and brain. Compared with non-small-cell lung cancer (NSCLC) SCLC has a unique natural history with a …

cancer
brain metastases
etoposide
lung cancer
liver metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location