Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8038 clinical trials
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

The 4SCAR-CD276-modified T cells (4SCAR-276) can recognize and kill tumor cells through the recognition of CD276, a surface protein expressed at high levels on many types of tumors but at low levels on normal tissues.

platelet count
tyrosine
neutrophil count
monoclonal antibodies
antibody therapy
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Tissue Retractors for Radiation Therapy of Head and Neck Tumors

The rate of therapy-associated side effects during and after radiotherapy of head and neck tumors is essential. The most effective approach to reducing acute toxicity is to cut out healthy tissue from the radiation field. The distance between the tumor and normal tissue can be individually increased using personalized, 3D …

dental caries
neck tumor
tumour resection
head and neck cancer
head and neck neoplasms
  • 0 views
  • 19 Feb, 2024
  • 1 location
RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors

This study is a multi-center, open-label, dose escalation study of RLY-1971 in subjects with advanced or metastatic solid tumors.

solid tumor
solid tumour
hair thinning
neuropathy
metastatic malignant solid tumor
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Meaning-Centered Intervention for Muslim Patients Who Are Being Treated for Advanced Cancer

This study will compare the effectiveness of the Masterful supportive care intervention with that of the non-faith-based active control supportive care intervention, which uses the American Cancer Society's patient education materials, for Muslim patients who have advanced cancers.

cancer
advanced cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
HER2-PREDICT: Translational Study of Tumor Samples From DS8201-A-U301 and DS8201-A-U302 Trials.

In order to identify mRNA ERBB2 levels, we will evaluate by gene expression tumor samples from these patients.

core needle biopsy
fine needle aspiration
cancer
erbb2
stage iv breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors

An ascending dose study in patients with solid tumors to evaluate the safety, tolerability, pharmacodynamics and efficacy of APG-1387 in combination with toripalimab. A phase II study of 3 cohorts will be included.

liver metastasis
antineoplastic
cancer
hair thinning
growth factor
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of AMG 650 in Adult Participants With Advanced Solid Tumors

To evaluate the safety and tolerability of AMG 650 in adult participants and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).

  • 0 views
  • 19 Feb, 2024
  • 3 locations
Impact of a Resource-based Life Review Intervention on Advanced Cancer Patients

The main objective of the present study is to evaluate the effects of the Revie intervention on the self-esteem of patients diagnosed with an advanced cancer. A pragmatic, two-arm parallel-group, waitlist randomized controlled trial is conducted. The study takes place in the oncology department of the University Hospitals of Geneva …

cancer
advanced cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of SBT6050 in Patients With Advanced HER2 Expressing Solid Tumors

A first-in-human (FIH) study using SBT6050 in HER2 expressing advanced malignancies

cancer
solid tumor
pembrolizumab
solid tumour
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.

Several studies have pointed out a potentially beneficial effect of metformin therapy in diabetic cancer patients. Several studies are investigating the anti-tumor effect of metformin in early breast cancer. However, the enhancing effect of metformin on anti-tumor immunity has only been demonstrated in animal models.

cancer
preoperative chemotherapy
breast carcinoma
metastasis
breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location