Metastatic Cancer Clinical Trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 549 clinical trials
Evaluation of Thiw he Gluw 'Akapi Substance Use Prevention Program

Researchers at the Centers for American Indian and Alaska Native Health in the Colorado School of Public Health at the University of Colorado completed an intensive community-engaged process to rigorously adapt the Strengthening Families Program for Parents and Youth 10-14 for the cultural context of a Northern Plains reservation community, …

suicide
substance use
drug abuse
substance use prevention
  • 0 views
  • 19 Feb, 2024
  • 1 location
Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC)

This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).

adjuvant
measurable disease
carcinoma
serum total bilirubin
serum bilirubin level
  • 0 views
  • 19 Feb, 2024
  • 1 location
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

karnofsky performance status
spinal cord
mri spine
melanoma
external beam radiation therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

This study aims to test the safety of hepatic artery infusion pump placement, a standard surgical procedure, and intraarterial chemotherapy initiation with the standard medication floxuridine (FUDR), using the Medtronic Synchromed II pump combined with the Codman arterial catheter in patients with unresectable (not removable by surgery) liver metastases from …

colorectal cancer
dexamethasone
cholangiocarcinoma
metastasis
liver metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

colorectal cancer
diarrhea
ct scan
metastasis
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 37 locations
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

This phase II trial studies how well liposome-encapsulated daunorubicin-cytarabine (CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by …

acute myeloid leukemia with myelodysplasia-related changes
cancer
myelodysplastic syndrome
myeloid leukemia
daunorubicin
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

measurable disease
advanced malignant solid tumor
cancer
gastric tumor
pembrolizumab
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

adjuvant
measurable disease
estrogen
cancer
keytruda
  • 8 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate ICP-022 in Patients With R/R PCNSL and SCNSL

The phase II clinical study is to investigate the safety, tolerability, efficacy and pharmacokinetics of ICP-022.

primary cns lymphoma
b-cell lymphoma
diffuse large b-cell lymphoma
lymphoma
  • 0 views
  • 19 Feb, 2024
  • 5 locations
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions

Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …

tumor recurrence
cancer
lung cancer
reirradiation
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location