Prostate Disorders Clinical Trials

A listing of Prostate Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 221 clinical trials
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis

Therefore, the primary objective of this trial is to compare if there is a difference between significant cancer detection rate in men undergoing prostate biopsies after MRI scan compared to men undergoing post-MRI prostate biopsies only after a shared decision-making based on prostate cancer risk estimation.

biopsy of prostate
cancer diagnosis
digital rectal examination
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

This is a Phase 3, multi-center, randomized, open-label, controlled study designed to evaluate the safety and efficacy of cabozantinib given in combination with atezolizumab versus a second novel hormonal therapy (NHT) in men with metastatic castration-resistant prostate cancer (mCRPC) who have previously been treated with one, and only one, NHT …

medical castration
progressive disease
prostate specific antigen
serum testosterone
hormonal therapy
  • 0 views
  • 19 Feb, 2024
  • 2 locations
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer

This study is trying to find out if the combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments lead to less side effects. This study is also looking at patient outcomes, quality of life, …

prostate adenocarcinoma
pelvic mri
brachytherapy
digital rectal examination
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

gonadotropin
bilateral orchidectomy
serum testosterone
metastatic hormone refractory prostate cancer
androgen suppression
  • 0 views
  • 19 Feb, 2024
  • 6 locations
MRI-guided Focal Laser Ablation

Magnetic resonance imaging-guided focal laser ablation of prostate cancer.

MRI
diffusion weighted imaging
prostate specific antigen
transrectal ultrasound
laser ablation
  • 0 views
  • 19 Feb, 2024
  • 1 location
18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer

To study the added value of 18F-PSMA-1007 PET to mpMRI in the detection of local prostate cancer lesions.

positron emission tomography
multiparametric magnetic resonance imaging
pet/ct scan
digital rectal examination
  • 0 views
  • 19 Feb, 2024
  • 1 location
PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy)

Open-label, multicenter, dose titration and expansion three-arm trial to evaluate the safety, tolerability, immunogenicity, and preliminary efficacy of W_pro1 cancer vaccine (W_pro1) in patients with metastatic castration resistant prostate cancer (mCRPC) W_pro1 in combination with goserelin acetate with or without cemiplimab, in patients with high-risk, localized prostate cancer (LPC)

corticosteroids
gonadotropin
squamous cell carcinoma of the skin
systemic therapy
bladder cancer
  • 2 views
  • 19 Feb, 2024
  • 16 locations
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

adenocarcinoma
stereotactic body radiation therapy
metastasis
hbed-cc
adenocarcinoma of prostate
  • 16 views
  • 19 Feb, 2024
  • 1 location
Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer

This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients with prostate cancer. All patients in the study will receive EPI-7386. Since this is the first study of EPI-7386 in humans, there is no information about how it affects people …

progressive disease
metastasis
bone scan
metastatic castration-resistant prostate cancer
diphosphonates
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Lutetium-177-PSMA-I&T in Oligo-metastatic Hormone Sensitive Prostate Cancer

  Radioligand therapy (RLT) using Lutetium-177 labelled PSMA is a promising new therapeutic approach to treat metastatic prostate cancer. This tumor-specific treatment is directed against prostate-specific membrane antigen (PSMA), which is overexpressed in prostate cancer cells.

finasteride
bicalutamide
docetaxel
castration-sensitive prostate cancer
white blood cell count
  • 4 views
  • 19 Feb, 2024
  • 4 locations