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A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study consists of two parts. In Part A, patients will receive MRG002 as a monotherapy at doses of 2.2, 2.6, or 3.0 mg/kg intravenously (IV) over 60-90 minute on Day 1 of every 3 weeks (Q3W), to determine the maximum tolerated dose (MTD) and recommended phase II dose (RP2D). In part B, patients will receive a single IV infusion of MRG002 at RP2D on Day 1 of Q3W.

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Study details
    Advanced Solid Tumors
    Advanced or Metastatic Gastric Cancer
    Advanced or Metastatic Gastroesophageal Junction Cancer

NCT04492488

Shanghai Miracogen Inc.

19 February 2024

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