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Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers RT-CAMSS Study

Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers RT-CAMSS Study

Recruiting
18 years and older
All
Phase 1/2

PRIMARY OBJECTIVES:

I. Develop and refine a real-time chemo-associated side effects monitoring support system (RT-CAMSS) using interactive text messaging (TXT) and mobile platforms for patients with gastric, esophageal, pancreatic and colorectal cancer during chemotherapy.

II. Assess the feasibility and engagement of the RT-CAMSS in a 2-month pilot study.

III. To gather preliminary data on the impact of RT-CAMSS on patient's quality of life and symptom distress.

OUTLINE

PHASE I: Patients participate in an audio-recorded focus group or one-on-one interview over 40 minutes either in-person, over the phone, or electronically. Patients receive sample text messages and questionnaires generated from the RT-CAMSS to generate reaction, discussion, and PRIMARY OBJECTIVES:

I. Develop and refine a real-time chemo-associated side effects monitoring support system (RT-CAMSS) using interactive text messaging (TXT) and mobile platforms for patients with gastric, esophageal, pancreatic and colorectal cancer during chemotherapy.

II. Assess the feasibility and engagement of the RT-CAMSS in a 2-month pilot study.

III. To gather preliminary data on the impact of RT-CAMSS on patient's quality of life and symptom distress.

OUTLINE

PHASE I: Patients participate in an audio-recorded focus group or one-on-one interview over 40 minutes either in-person, over the phone, or electronically. Patients receive sample text messages and questionnaires generated from the RT-CAMSS to generate reaction, discussion, and scenarios.

PHASE II: Patients receive RT-CAMSS over 2 months or until chemotherapy is discontinued, whichever is earlier. RT-CAMSS consists of text messages addressing knowledge about specific cancer type and chemotherapy, side-effect prevention, suggestions of lifestyle behavioral changes and emotional support, and preparation for surgery. Patients then record their symptoms through answering a series of questionnaires and receive tailored feedback according to their answers, including a consultation with a nurse.

After completion of study, patients are followed up at 1 and 2 months.

Study details
    Clinical Stage IV Gastric Cancer AJCC v8
    Clinical Stage IVA Gastric Cancer AJCC v8
    Clinical Stage IVB Gastric Cancer AJCC v8
    Pathologic Stage IV Gastric Cancer AJCC v8
    Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8
    Stage IV Colorectal Cancer AJCC v8
    Stage IVA Colorectal Cancer AJCC v8
    Stage IVB Colorectal Cancer AJCC v8
    Stage IVC Colorectal Cancer AJCC v8
    Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
    Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
    Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8
    Stage III Pancreatic Cancer AJCC v8
    Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8
    Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage 0 Gastric Cancer AJCC v8
    Clinical Stage I Esophageal Adenocarcinoma AJCC v8
    Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage I Gastric Cancer AJCC v8
    Clinical Stage II Esophageal Adenocarcinoma AJCC v8
    Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage II Gastric Cancer AJCC v8
    Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
    Clinical Stage IIA Gastric Cancer AJCC v8
    Clinical Stage IIB Gastric Cancer AJCC v8
    Clinical Stage III Esophageal Adenocarcinoma AJCC v8
    Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage III Gastric Cancer AJCC v8
    Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
    Clinical Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage 0 Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage 0 Gastric Cancer AJCC v8
    Pathologic Stage I Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage I Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage I Gastric Cancer AJCC v8
    Pathologic Stage IA Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IA Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IA Gastric Cancer AJCC v8
    Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IB Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IB Gastric Cancer AJCC v8
    Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage II Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage II Gastric Cancer AJCC v8
    Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IIA Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IIA Gastric Cancer AJCC v8
    Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IIB Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IIB Gastric Cancer AJCC v8
    Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage III Gastric Cancer AJCC v8
    Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IIIA Gastric Cancer AJCC v8
    Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
    Pathologic Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8
    Pathologic Stage IIIB Gastric Cancer AJCC v8
    Pathologic Stage IIIC Gastric Cancer AJCC v8
    Pathologic Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
    Stage 0 Colorectal Cancer AJCC v8
    Stage 0 Pancreatic Cancer AJCC v8
    Stage I Colorectal Cancer AJCC v8
    Stage I Pancreatic Cancer AJCC v8
    Stage IA Pancreatic Cancer AJCC v8
    Stage IB Pancreatic Cancer AJCC v8
    Stage II Colorectal Cancer AJCC v8
    Stage II Pancreatic Cancer AJCC v8
    Stage IIA Colorectal Cancer AJCC v8
    Stage IIA Pancreatic Cancer AJCC v8
    Stage IIB Colorectal Cancer AJCC v8
    Stage IIB Pancreatic Cancer AJCC v8
    Stage IIC Colorectal Cancer AJCC v8
    Stage III Colorectal Cancer AJCC v8
    Stage IIIA Colorectal Cancer AJCC v8
    Stage IIIB Colorectal Cancer AJCC v8
    Stage IIIC Colorectal Cancer AJCC v8
    Stage IV Pancreatic Cancer AJCC v8

NCT04449679

Thomas Jefferson University

24 November 2025

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