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Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

Recruiting
18 years and older
Male
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)
OUTLINE

Patients receive standard of care radium Ra 223 dichloride given by intravenous (IV) bolus every 4 weeks for up to 6 cycles. Patients undergo collection of blood every 1-3 months during radium Ra 223 dichloride treatment.

After completion of study, patients are followed up every 3 months for up to 5 years from the date of treatment completion.

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Study details
    Metastatic Prostate Carcinoma
    Stage IV Prostate Cancer AJCC v8
    Stage IVB Prostate Cancer AJCC v8
    Stage IVA Prostate Cancer AJCC v8
    Castration-Resistant Prostate Carcinoma
    Metastatic Malignant Neoplasm in the Bone

NCT04489719

University of Washington

19 February 2024

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