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Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients

Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients

Recruiting
15-60 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This is a phase 3, open label, single arm, multi-center study in newly diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL patients who have myeloid or stem cell markers. The patients will receive decitabine combined with HAAG regimen in the induction treatment. The patients who respond to induction chemotherapy will undergo consolidation chemotherapy, and an optional allogeneic hematopoietic stem cell transplantation and post-transplantation maintenance treatment with decitabine according to patient's wishes.

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Study details
    Chemotherapy
    Chemotherapy
    T-cell acute lymphoblastic leukemia
    T-cell Lymphoblastic Lymphoma Leukemia
    T-cell/Myeloid Mixed Phenotype Acute Leukemia

NCT04446130

The First Affiliated Hospital of Soochow University

19 February 2024

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