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CPX-351 in Higher Risk Myelodysplastic Syndromes

CPX-351 in Higher Risk Myelodysplastic Syndromes

Recruiting
18-70 years
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

A phase I/II study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure.

CPX-351 is an advanced liposomal formulation of daunorubicin and cytarabine encapsulated at a 1:5 ratio.

Patients will receive induction treatment with CPX-351. Patients in response (complete response (CR), complete response with incomplete hematologic improvement (CRi), partial response (PR)) after induction will receive monthly courses of consolidation therapy with CPX-351.

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Study details
    Preleukemia
    MYELODYSPLASTIC SYNDROME

NCT04273802

Groupe Francophone des Myelodysplasies

19 February 2024

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