Diagnostic Performance of a New Method for the Echocardiographic Assessment of Coronary Arteries Abnormalities

  • STATUS
    Recruiting
  • participants needed
    4000
  • sponsor
    ITAB - Institute for Advanced Biomedical Technologies
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Updated on 19 February 2024
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Summary

Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and right. To overcome the echocardiographic limitations, the investigators designed, studied and implemented in our Institute a specific echocardiographic-based two-dimensional non-Doppler 4-views approach for the diagnosis of CAA.

Description

The method consisted of 4-CAA-focused specific views, routinely available from any echocardiographic exam: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views. PSAX, the traditional approach, along with the PLAX, and the apical 4/5-chambers views.

A hallmark of CAA was considered the absence of a proper visualization of the origin of the coronary arteries from the aortic root. In addition, the presence of the ring sign, visualized from the PLAX was considered as abnormal. This sign is of interest when an aberrant left or right CAA is suspected. A coronary artery originating from the contralateral aortic sinus, along its intramural course, crosses the mid-anterior line of the circular aorta to reach the sinus of Valsalva of its intended origin. Consequently, its cross-section should be visible in an orthogonal view traversing the mid-long axis of the aorta, namely the parasternal long-axis view.

Details
Condition Coronary Artery Anomaly
Age 100years or below
Treatment Echocardiographic assessment of coronary arteries origin and proximal course
Clinical Study IdentifierNCT04224090
SponsorITAB - Institute for Advanced Biomedical Technologies
Last Modified on19 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

patients undergoing their first echocardiographic examination

Exclusion Criteria

already known congenital heart disease and cardiomyopathies
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