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Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas

Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas

Recruiting
1-95 years
All
Phase N/A

Precise classification based on molecular and genetic biomarkers/subgroups for gliomas is challenging. This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and genetic data (Whole exome sequencing, RNA sequencing, proteomics, etc). This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.

Study details
    Mutation
    Glioma
    Molecular Sequence Variation

NCT04216537

The First Affiliated Hospital of Zhengzhou University

19 February 2024

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