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Inflammation and Cardiovascular Health in Women

Inflammation and Cardiovascular Health in Women

Recruiting
40-79 years
Female
Phase N/A

The goals of this study are to better understand ways in which HIV infection-incited systemic immune activation and inflammation augment MI risk among women. To this end, WHIV and non-HIV-infected women will undergo structural and functional cardiovascular imaging studies (Cardiac PET, 99mTc-tilmanocept SPECT/CT, Contrast Enhanced Coronary and Aortic Computed Tomography Angiography) as well as vascular, metabolic/hormonal, and immune phenotyping. Measures of immune activation, arterial inflammation, and cardiovascular pathology will be compared between groups and interrelationships between these parameters will be assessed among WHIV.

Study details
    Myocardial Infarction
    Ischemic Heart Disease
    HIV/AIDS

NCT04224181

Massachusetts General Hospital

19 February 2024

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