In recent years, with the successful application of ICG fluorescence imaging technology in laparoscopic equipment, scholars have found that ICG near infrared imaging has better tissue penetration and can better identify lymph nodes in hypertrophic adipose tissue than other dyes under visible light, which makes ICG fluorescence imaging guide laparoscopic radical resection of gastric cancer lymph node dissection has become a new exploration direction. ICG near-infrared imaging technology has important research value, good application prospect and broad development space in laparoscopic radical resection of gastric cancer. However, at present, the application of ICG near infrared imaging technology in laparoscopic radical resection of gastric cancer is still in the exploratory stage, and there is no unified standard.Therefore, in the world, there is still a lack of high-level evidence-based evidence of large-sample prospective randomized controlled trials to evaluate the effectiveness, safety and feasibility of submucosal or subserous injection of ICG in guiding laparoscopic D2 radical resection of gastric cancer.The investigator first carried out this study in the world to evaluate the lymph node acquisition and perioperative safety of gastric cancer patients who received submucosal injection of ICG and subserous injection of ICG during laparoscopic radical gastrectomy in the same period, in order to promote the standardized development of ICG near infrared imaging in laparoscopic radical gastrectomy.