Blood Biomarker of Alzheimer's Disease (AD)

  • STATUS
    Recruiting
  • participants needed
    60
  • sponsor
    Duke University
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Updated on 20 September 2024
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cancer
alzheimer's disease
blood test
memory disorders
Accepts healthy volunteers

Summary

Currently, no cures or disease modifying therapies exist for Alzheimer's disease (AD). This is partially due to the inability to detect the disease before it has progressed to a stage where there are clinical manifestations. The identification and validation of high throughput biomarkers to measure disease progression (as well as identify pre-clinical disease onset) is critical to the development of disease-modifying or even preventative therapies. In this study, we are testing a blood biomarker for stratification of Alzheimer's disease patients and healthy volunteers. This study may lead to future blood tests that may help earlier diagnosis of Alzheimer's disease and detect the disease progression.

Details
Condition Alzheimer's Disease
Age 50years - 100years
Clinical Study IdentifierNCT03340571
SponsorDuke University
Last Modified on20 September 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Alzheimer's Disease Patients
years and older
AD patient who is seen at the Memory Disorders Clinic
AD diagnosis
Non smoking
No cancer treatment in the last 5 years
Informed consent from the patient or the patient's legally authorized representative (LAR)
Patient and/or LAR able to read and speak English
Healthy Control Participants
years and older
Non smoking
No cancer treatment in the last 5 years
Age matched to AD subject
Able to read and speak English

Exclusion Criteria

Alzheimer's Disease Patients
Known additional neurological disease
Healthy Control Participants
Neurological degenerative diseases (such as Parkinson's, Alzheimer's or Huntington's)
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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