MMAPPIN' Study: Multiple Myeloma Analysis For Patient-specific Insights to Dissect Disease Heterogeneity

  • STATUS
    Recruiting
  • End date
    Sep 29, 2032
  • participants needed
    520
  • sponsor
    IRCCS Azienda Ospedaliero-Universitaria di Bologna
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Updated on 15 June 2026
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Summary

This is a single-center, observational study in patients with multiple myeloma, conducted both retrospectively and prospectively. The study aims to improve understanding of the biological and clinical factors that influence disease progression, relapse, and treatment resistance.

The study will integrate clinical information with advanced genomic and molecular analyses, including whole genome and RNA sequencing, as well as circulating tumor markers, to identify features linked to therapy response and disease behavior. All data will be securely stored, maintaining patient confidentiality, to build a comprehensive map of multiple myeloma that may guide more personalized future treatments.

Details
Condition Myeloma Multiple
Age 18years or above
Clinical Study IdentifierNCT07582354
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Last Modified on15 June 2026

Eligibility

 Yes No Not Sure

Inclusion Criteria

Age 18+
Signed CI for study partecipation and personal data processing
Diagnosis of monoclonal gammopathy, or of acrive multiple myaloma (NDMM/RMM/RRMM)

Exclusion Criteria

None
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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