Exploring the Clinical Application Value of CAIX-Targeted PET Imaging in Renal Cancer Patients

  • STATUS
    Recruiting
  • End date
    Sep 30, 2026
  • participants needed
    113
  • sponsor
    The First Affiliated Hospital of Xiamen University
Send
Updated on 5 May 2025
Accepts healthy volunteers

Summary

To evaluate the efficacy of targeted CAIX-specific probe PET imaging in the diagnosis and staging of kidney cancer, as well as to assess its role in prognosis prediction and treatment evaluation for kidney cancer.

Description

Images will be analyzed by at least two physicians with extensive experience in nuclear medicine and radiological diagnostics. Regions of interest (ROIs) will be delineated for the lesion tissues to measure volume and SUV values. The interpreted PET/CT imaging results will be compared to the corresponding histopathological results of the lesions (obtained through biopsy or surgery) and will be used as the reference standard. We will employ McNemar's test to compare the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of targeted CAIX PET/CT imaging and enhanced CT in primary tumors, metastatic lymph nodes, and distant metastatic lesions.

Details
Condition Tumor, Carbonic Anhydrase IX
Age 18years - 74years
Clinical Study IdentifierNCT06956144
SponsorThe First Affiliated Hospital of Xiamen University
Last Modified on5 May 2025

Eligibility

How to participate?

Step 1 Connect with a study center
Message sent successfully.56
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.57
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.58
Sign up59

Send a message24

Enter your contact details to connect with study team25

Investigator Avatar

Primary Contact26

First name*27
Last name*30
Email*33
Phone number*37
Preferred way of contact label
Race
Ethnicity
Other language43

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Browse trials for

Accepts healthy volunteers

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.