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Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

Recruiting
25-65 years
All
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

This is a randomised, double-blind, cross-over study. Participants will be randomly assigned to receive either moxonidine 0.4mg daily or amlodipine 5mg and will later receive the alternate treatment.

Comprehensive testing will occur after each 12 week treatment phase and will include assessment of muscle sympathetic nerve activity, gut microbiome analysis and metabolic markers.

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Study details
    Vascular Diseases
    Vascular Diseases
    Hypertension
    Obesity
    Obesity

NCT04474899

Royal Perth Hospital

19 February 2024

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